Nutritional Intervention: Antioxidants for Optimum Health and Modulation of the Toxicity of Environmental Pollutants
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It is generally well known that nutrition and lifestyle choices are modulators of chronic diseases.

A relatively new nutritional paradigm has been developed in environmental toxicology with an aim to understand the relationship between nutrition, exposure to environmental toxicants, and disease. Nutrition may be the most practical way to develop intervention and prevention strategies for diseases associated with exposure to environmental toxicants. The onset and development of chronic diseases is a complex process that may be influenced by exposure to environmental pollutants, a sedentary lifestyle, and poor dietary habits. The development of chronic disease typically progresses from the onset of oxidative stress at the cellular level and leads to chronic inflammation. Both lifestyle factors and exposure to pollutants can influence the incidence and progression of disease. Our modern diet includes the overconsumption of processed and refined foods that are high in inflammatory fatty acids which can make diet induced metabolic complications worse, and also exacerbate pollutant-associated inflammation processes. Oxidative stress and inflammation can be reduced through diet by including the consumption of fruits and vegetables that are rich in antioxidants and anti-inflammatory components. Exposure to environmental pollutants has been linked to the development of many chronic diseases including cardiovascular disease, diabetes, and metabolic syndrome. Emerging evidence suggests that nutrition can both positively and negatively modulate the toxic effects of pollutant exposure. For example, high fat diets that increase inflammation can exacerbate pollutant toxicity, while diets rich in anti-inflammatory food components such as omega-3 fatty acids from fish and plant-derived polyphenols can attenuate toxicant-associated inflammation. Additionally, studies have shown that the harmful effects of air pollution may be modified by intake of essential micronutrients (B vitamins, and vitamins C, D, and E) and omega-3 fatty acids. Folic acid supplementation has also been shown to be effective in folate deficient individuals to lower blood arsenic levels through methylation of arsenic to di-methylated species that facilitates renal elimination. This presentation will summarize the available evidence supporting that diets rich in antioxidants and anti-inflammatory nutrients can improve overall health status, and for individuals exposed to chemical stressors, decrease vulnerability to disease processes.

Publication Summary

  • Geosyntec Authors: Lance Fontenot
  • All Authors: Lance Fontenot
  • Title: Louisiana Environmental Conference and Trade Fair
  • Event or Publication: Event
  • Practice Areas: Environmental Planning and Management
  • Citation: Lance Fontenot, Ph.D. (Louisiana) will present "Nutritional Intervention: Antioxidants for Optimum Health and Modulation of the Toxicity of Environmental Pollutants," and Kaitlyn Rhonehouse, P.E. (North Carolina) and Mark Johnson (Maryland) will present "Navigating the Phase I and Phase II Environmental Site Assessment Process" at the Louisiana Environmental Conference and Trade Fair at the Cajundome Convention Center in Lafayette, Louisiana on March 19, 2020.
  • Date: March 19, 2020
  • Location: Lafayette, Louisiana
  • Publication Type: Platform Presentation